EUGENE, Ore. » Marcus Mariota got his curtain call at Autzen Stadium.

With the 44-10 victory already in hand Saturday against Colorado, No. 3 Oregon sent its Heisman-hopeful quarterback out for the first snap of the fourth quarter.

That allowed the fans a chance to give Mariota a standing ovation when he handed off the rest of the game to backup Jeff Lockie. The crowd chanted "Mar-i-o-ta!"

The game may have been Mariota’s last at home in Eugene. The junior has one more season of eligibility left, although it’s widely expected that he’ll head for the NFL Draft when this season is over.

"If this is my last game at Autzen it was truly special," he said, "and something I’ll keep close to my heart for the rest of my life."

Mariota threw for 323 yards and three touchdowns and ran for 73 yards and another score against Colorado, giving him 42 total touchdowns this season to set a Pac-12 record.

Freshman Royce Freeman ran for 105 yards and two additional scores for the Ducks (10-1, 7-1 Pac-12). Oregon has already clinched the North Division’s berth in the conference championship game on Dec. 5.

Colorado (2-9, 0-8) has lost seven straight since beating Hawaii 21-12 on Sept. 20.

Mariota, who has thrown a touchdown pass in every game of his career at Oregon, has not yet said what his postseason plans are. Should he go to the NFL, he is projected by many as a top-five pick.

He has thrown 32 touchdowns this season with just two interceptions and leads the nation in quarterback rating. With 42 total touchdowns this season (32 passing, 9 rushing and 1 TD catch), he passed former USC quarterback Matt Barkley (41) for the Pac-12’s single-season record.

"I couldn’t have done it without all those guys in the locker room," Mariota said. "To me, it is what it is — a number. I’m sure another guy will come around in the next couple of years and break it."

Against Colorado, Mariota became the fifth in an exclusive group of quarterbacks who have thrown for 9,000 yards and run for another 2,000. Among the names on that list are Tim Tebow and Colin Kaepernick.

Coach Mark Helfrich patted Mariota on the helmet when he reached the sidelines after his one snap in the fourth quarter.

Asked about the plan to give Mariota a chance for a last Autzen ovation, Helfrich said: "I think that kind of explains itself."

No. 2 ALABAMA 48, WESTERN CAROLINA 14

TUSCALOOSA, Ala. » Derrick Henry rushed for two TDs and scored a third on a catch, all in the first half, to lead the Crimson Tide (10-1) over the Catamounts (7-5).

No. 4 MISSISSIPPI STATE 51, VANDERBILT 0

STARKVILLE, Miss. » Dak Prescott threw three touchdown passes and ran for another to lead the Bulldogs (10-1, 6-1 Southeastern Conference) over the Commodores (3-8, 0-7).

It was a dominant performance by the Bulldogs, who finished undefeated at Davis Wade Stadium for the first time since 1999.

No. 6 BAYLOR 49, OKLAHOMA STATE 28

WACO, Texas » Bryce Petty threw touchdown passes on Baylor’s first two drives that took less than a minute combined, putting the Bears (9-1, 6-1 Big 12) ahead to stay in a comfortable victory over the Cowboys (5-6, 3-5).

Playoff-contending Baylor won its 15th consecutive home game on a dreary and rainy night along the banks of the Brazos River, staying in a three-way tie with No. 5 TCU and No. 12 Kansas State for the Big 12 lead with two games left.

No. 7 OHIO ST. 42, INDIANA 27

COLUMBUS, Ohio » Jalin Marshall returned a punt 54 yards for a touchdown to give Ohio State the lead late in the third quarter and added three late insurance scores to lead the Buckeyes (10-1, 7-0 Big Ten) past the Hoosiers (3-8, 0-7).

The surprisingly tight game for most of the day could impact the playoff hopes of the Buckeyes, who clinched the East Division and a berth in the conference title game.

ARKANSAS 30, No. 8 MISSISSIPPI 0

FAYETTEVILLE, Ark. » Rohan Gaines returned an interception 100 yards for a score, and Arkansas’ defense forced six turnovers against the Rebels (8-3, 4-3).

The win earned the Razorbacks (6-5, 2-5 Southeastern), losers of 17 straight SEC games until a victory over LSU last week, bowl eligibility for the first time in three seasons.

No. 9 GEORGIA 55, CHARLESTON SOUTHERN 9

ATHENS, Ga. » Georgia scored two touchdowns on its first three snaps, including an 83-yard run by Nick Chubb, and the Bulldogs rolled past the Buccaneers (8-4).

No. 10 MICHIGAN STATE 45, RUTGERS 3

EAST LANSING, Mich. » Jeremy Langford and Tony Lippett celebrated senior day in style as the Spartans (9-2, 6-1 Big Ten) smashed the Scarlet Knights (6-5, 2-5).

No. 11 UCLA 38, No. 24 USC 20

PASADENA, Calif. » Brett Hundley passed for 326 yards and three touchdowns and rushed for another score, leading the Bruins (9-2, 6-2 Pac-12) past the Trojans (7-4, 6-3) for UCLA’s third straight victory in the annual crosstown showdown.

Devin Lucien, Thomas Duarte and Eldridge Massington caught scoring passes as the Bruins confirmed their Los Angeles supremacy and closed in on the Pac-12 South title with a one-sided romp over their biggest rivals at a festive Rose Bowl.

UCLA can advance to the Pac-12 title game against No. 3 Oregon with a victory over Stanford on Friday.

No. 13 ARIZONA STATE 52, WASHINGTON STATE 31

TEMPE, Ariz. » Taylor Kelly threw for four touchdowns in his last home game and the Sun Devils (9-2, 6-2 Pac-12) dominated the second half against the Cougars (3-8, 2-6).

No. 14 WISCONSIN 26, IOWA 24

IOWA CITY, Iowa » Melvin Gordon surpassed 2,000 yards rushing with 200 yards and two touchdowns, and the Badgers (9-2, 6-1 Big Ten) held off the Hawkeyes (7-4, 4-3) for their sixth straight win.

Gordon became the 17th FBS player with a 2,000-yard rushing season. The Badgers have to beat Minnesota in Madison next weekend to earn a shot at Ohio State in the Big Ten title game.

No. 15 ARIZONA 42, No. 20 UTAH 10

SALT LAKE CITY » Freshman Nick Wilson ran for 218 yards and three touchdowns as the Wildcats (9-2, 6-2 Pac-12) overcame an injury to quarterback Anu Solomon and pulled away from the Utes (7-4, 4-4).

No. 16 AUBURN 31, SAMFORD 7

AUBURN, Ala. » Cameron Artis-Payne ran for 129 yards and a touchdown, Nick Marshall passed for 171 yards and a score, and the Tigers (8-3) snapped a two-game skid with a victory over the Bulldogs (7-4).

Auburn (8-3) used the game against an FCS opponent to tune up for next week’s Iron Bowl showdown at No. 2 Alabama.

No. 18 MARSHALL 23, UAB 18

BIRMINGHAM, Ala. » Defensive lineman Ra’shawde Myers recovered a fumble in the end zone for a go-ahead touchdown with 8:20 left, and the Thundering Herd (11-0, 7-0 Conference USA) stayed unbeaten by rallying past the Blazers (5-6, 3-4).

No. 19 MISSOURI 29, TENNESSEE 21

KNOXVILLE, Tenn. » Maty Mauk threw a pair of touchdown passes and Marcus Murphy ran for two scores as the Tigers (9-2, 6-1 Southeastern) defeated the Volunteers (5-6, 2-5) to maintain control of the SEC East race.

The Tigers set a school record with their 10th straight road win.

Missouri can clinch the East Division and earn a second straight trip to the SEC championship game by winning at home Friday over Arkansas. A loss would send No. 9 Georgia to Atlanta instead.

MINNESOTA 28, No. 21 NEBRASKA 24

LINCOLN, Neb. » Briean Boddy-Calhoun ripped the ball out of Nebraska receiver De’Mornay Pierson-El’s hands at the Minnesota 2-yard line after Mitch Leidner scored the go-ahead touchdown, and the Golden Gophers (8-3, 5-2) overcame a 14-point halftime deficit to defeat the Cornhuskers (8-3, 4-3).

The Gophers can win the Big Ten West and go to the conference title game on Dec. 6 with a victory at Wisconsin next weekend.

No. 22 COLORADO STATE 58, NEW MEXICO 20

FORT COLLINS, Colo. » Dee Hart matched a school record with six touchdowns and the Rams (10-1, 6-1 Mountain West) amassed a program-best 698 yards of offense in routing the Lobos (3-8, 1-6) to extend their winning streak to nine games.

The Rams are off to their best start since 1994. Hart led the way against New Mexico by rushing for 230 yards and five TDs. He also hauled in a TD pass to tie Kapri Bibbs’ school mark of six scores set last season against the Lobos.

No. 23 OKLAHOMA 44, KANSAS 7

NORMAN, Okla. » Oklahoma freshman Samaje Perine set a major college record by running for 427 yards in a driving rainstorm, scoring five touchdowns and leading the Sooners (8-3, 5-3 Big 12) over the Jayhawks (3-8, 1-7).

A week after Wisconsin’s Melvin Gordon set the mark by rushing for 408 yards against Nebraska, Perine ran past him. He broke the 7-day-old record on his 34th and final carry, a 42-yard run with 12:16 left.