NEW YORK >> As usual, Big Papi was in the pink against the New York Yankees.

David Ortiz homered twice, passing Hall of Famer Carl Yastrzemski for second place on Boston’s career list, and Steven Wright pitched a three-hitter as the Red Sox beat the Yankees 5-1 on Sunday night.

Swinging a pink bat and wearing pink wrist bands for Mother’s Day, Ortiz hit two long solo shots off a struggling Luis Severino. And in his farewell season, the 40-year-old Ortiz has already been a major New York nemesis again: He has five home runs against the Yankees since April 29, giving him 52 in his career — all but one with the Red Sox.

Dustin Pedroia lofted an early two-run homer and Xander Bogaerts also went deep for the Red Sox, who prevented a three-game sweep and won for the fourth time in six meetings with their longtime rivals this year.

Wright (3-3) walked one and struck out seven, sailing to his first complete game in 17 major league starts and lowering his ERA to 1.52. He was two strikes from a shutout, too, when Brett Gardner homered with two outs in the ninth inning.

The knuckleballer hardly got rattled, whiffing pinch-hitter Ronald Torreyes with his 101st pitch to end it.

“It definitely helps when the wind’s not blowing as hard. There was a little bit of breeze but it was almost like throwing inside,” Wright said.

Mixing his 73-75 mph knuckleballs with the occasional 87 mph fastball, Wright baffled the last-place Yankees all night. When he threw something soft, they seemed to hit it even softer. When he dialed up a heater, they swung late and missed.

“He was really good. He’s been great all year,” Yankees catcher Brian McCann said. “I felt like he could do whatever he wanted tonight with the ball.”

Ortiz connected in the fourth and seventh to give him three homers in five at-bats against Severino (0-5) since the righty made his big league debut against Boston last August.

Big Papi has hit 454 of his 512 career homers with the Red Sox, moving him ahead of Yastrzemski (452) and leaving Ortiz behind only Ted Williams (521) on the franchise list.

“You’re starting to get into names that are historic. A great career. And no signs of slowing down,” Boston manager John Farrell said.