Max Holloway’s fight against Anthony Pettis will be the main event of UFC 206 for the interim 145-pound title on Dec. 10, the UFC announced Saturday night.
The original main event between light heavyweight champion Daniel Cormier and challenger Anthony Johnson was canceled earlier this week because of an injury to Cormier.
The winner between Holloway and Pettis will fight Jose Aldo to unify the 145-pound titles.
Conor McGregor, who held both the 145- and 155-pound belts after beating Eddie Alvarez for the lightweight title earlier this month, has been stripped of his featherweight title.
Aldo takes over as champion after winning the interim title against Frankie Edgar in July.
UFC 206 will take place in Toronto, Canada, and be available on pay-per-view.
Holloway will join Hilo’s B.J. Penn as the only fighters from Hawaii to headline a UFC PPV event.
Holloway defeated Charles Oliveira in the main event of a UFC Fight Night card in August 2015.