WASHINGTON >> President Donald Trump launched a crude Twitter attack on the brains, looks and temperament of a female TV personality today, drawing bipartisan howls of outrage and leaving fellow Republicans beseeching him: Stop, please just stop.

Trump’s tweets aimed at MSNBC’s Mika Brzezinski revived concerns about his views of women in a city where civility already is in short supply and he is struggling for any support he can get for his proposals on health care, immigration and other controversial issues.

“I heard poorly rated Morning—Joe speaks badly of me (don’t watch anymore),” Trump tweeted to his nearly 33 million followers Thursday morning. “Then how come low I.Q. Crazy Mika, along with Psycho Joe, came to Mar-a-Lago 3 nights in a row around New Year’s Eve, and insisted on joining me. She was bleeding badly from a face-lift. I said no!”

The tweets served to unite Democrats and Republicans for once in a chorus of protest that amounted to perhaps the loudest outcry since Trump took office.

“Obviously I don’t see that as an appropriate comment,” said Republican House Speaker Paul Ryan. House Democratic leader Nancy Pelosi called Trump’s tweets, “blatantly sexist.” The president, she added, “happens to disrespect women … it’s sad.”

I heard poorly rated @Morning_Joe speaks badly of me (don't watch anymore). Then how come low I.Q. Crazy Mika, along with Psycho Joe, came..

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— Donald J. Trump (@realDonaldTrump) June 29, 2017

…to Mar-a-Lago 3 nights in a row around New Year's Eve, and insisted on joining me. She was bleeding badly from a face-lift. I said no!

— Donald J. Trump (@realDonaldTrump) June 29, 2017

Republican Sen. James Lankford of Oklahoma even linked the president’s harsh words to the June 14 shootings of House Majority Whip Steve Scalise and three others.

“The president’s tweets today don’t help our political or national discourse and do not provide a positive role model for our national dialogue,” Lankford said, noting that he had just chaired a hearing on the shootings.

On Trump’s level of insult-trading, Brzezinski responded on Twitter by posting a photograph of a Cheerios box that included the phrase “made for little hands.” People looking to get under the president’s skin have long suggested that his hands appear small for his frame.

Trump’s allies cast his outburst as positive, an example of his refusal to be bullied.

White House spokeswoman Sarah Huckabee Sanders said the president was “pushing back against people who have attacked him day after day after day. Where is the outrage on that?”

“The American people elected a fighter; they didn’t elect somebody to sit back and do nothing,” she added.

First lady Melania Trump, who has vowed to fight cyberbullying while her husband is president, gave his tweets a pass.

“As the first lady has stated publicly in the past, when her husband gets attacked, he will punch back 10 times harder,” her communications director, Stephanie Grisham, said in a statement.

As Trump welcomed South Korean President Moon Jae-in for a White House dinner Thursday evening, he did not respond to shouted questions from reporters about whether he regretted the tweet.

Some of the administration’s most high-profile women — daughter and presidential assistant Ivanka Trump, Counselor Kellyanne Conway and Deputy National Security Adviser Dina Powell — did not respond to requests for comment.

The White House has shown increasing irritation over harsh coverage of the president on Brzezinski and Scarborough’s “Morning Joe,” including commentary questioning Trump’s mental state.

About two hours before his tweets, Brzezinski said on the show that “it’s not normal behavior” for any leader to be tweeting about people’s appearances or to be bullying, lying, undermining managers and throwing people under the bus. She said that if any business executive behaved the way Trump does, “there would be concern that perhaps the person who runs the company is out of his mind.”

On Wednesday, she had mocked Trump after a story in The Washington Post said he had posted fake Time magazine covers of himself in some of his golf resorts.

“Nothing makes a man feel better than making a fake cover of a magazine about himself, lying every day and destroying the country,” Brzezinski said.

Trump, who has a habit of throwing up distractions to deflect bad news, has been straining to advance his agenda lately, with the Senate this week coming up short in finding enough votes to begin debate on a bill to roll back President Barack Obama’s health care law.

His demeaning broadside against a woman raised new complaints among critics who have long accused him of sexism and inflaming tensions in a deeply polarized nation. Trump also has consistently stoked a long-running feud with the press that has not hurt him with his base of roughly a third of the electorate.

But one expert rejected the idea that Trump’s tweets about the MSNBC hosts amounted to a calculated push-back against the media.

“It’s not a critique of the press. It’s a diatribe. It’s a rant,” said Theodore L. Glasser, professor emeritus at Stanford University and an expert in mass media.

It wasn’t the first time Trump has assailed a television personality who is a woman. In 2015, he went after then-Fox News Channel host Megyn Kelly when she questioned him at a debate. Trump said later that during the exchange, Kelly had “blood coming out of her wherever.”

It’s also far from the only time he’s raised eyebrows with remarks about the physical attributes of women. Just this week in the Oval Office, Trump interrupted his phone conversation with the new prime minister of Ireland to remark on a “beautiful” Irish journalist in the room and take note of the “nice smile on her face.”

The latest flare-up did nothing to improve Trump’s chances of advancing the health care bill that formed a centerpiece of his campaign.

“This has to stop – we all have a job – 3 branches of gov’t and media,” tweeted Republican Susan Collins of Maine, a critic of the Senate GOP bill. “We don’t have to get along, but we must show respect and civility.”

Tweeted Republican Sen. Ben Sasse of Nebraska, a frequent Trump critic: “Please just stop. This isn’t normal and it’s beneath the dignity of your office.” Agreed South Carolina Republican Lindsey Graham: “Mr. President, your tweet was beneath the office and represents what is wrong with American politics, not the greatness of America.”

Brzezinski and Scarborough, who are engaged, have known Trump for years and interviewed him numerous times during the campaign. But they have been highly critical of Trump since he took office.

They did meet with Trump at his Florida estate on New Year’s Eve for what they described as a brief visit, and also spent time with the president and senior staff at the White House in February. But Brzezinski supporters disputed Trump’s characterization of the Mar-a-Lago meeting, saying it was the president who repeatedly asked the couple to visit him. Brzezinski and Scarborough were staying in the area for the holidays.

NBC News spokeswoman Lorie Acio said in a statement, “It’s a sad day for America when the president spends his time bullying, lying and spewing petty personal attacks instead of doing his job.”