A watershed moment has arrived for many families: This week health care workers from CVS and Walgreens, under contract from the federal government, will fan out to nursing homes across the country to begin vaccinating residents against the novel coronavirus. The shots not only will help protect the nation’s seniors and infirm — and the staff who care for them — but they raise the prospect of ending the devastating isolation many residents have felt for months.

Family members are hopeful that before too long they will return to visiting loved ones regularly. We checked with experts on some common questions.

Question: Will restrictions on visiting be lifted soon?

Answer: Probably not in a big way. Restrictions vary by state, and the federal government’s guidance on what it considers safe stands for now. They already allow visits under certain conditions. The Centers for Medicare & Medi­caid Services, or CMS, recommended in September that outdoor visits with residents be allowed and indoor visits, too, if the facility has been free of cases for 14 days.

Some medical experts have said that those guidelines are too lax and that visits should be severely restricted, even banned. However, some of these experts are now saying that the vaccine changes the equation, somewhat.

“Once all residents are vaccinated, it opens the door for loosening of restrictions,” said Dr. Michael Wasserman, immediate past president of the California Association of Long Term Care Medicine, a geriatrician and former executive at nursing home chains.

To allow visits, Wasserman recommends all residents of a nursing home should be vaccinated (unless they have some condition or allergy that would discourage vaccination on medical grounds); all staff members should be vaccinated; the nursing home should have the ability to ensure that visitors test negative for the coronavirus and have been disciplined about wearing a mask in public settings.

Q: Is the vaccine safe and effective for old and frail residents of nursing homes?

A: The clinical trials of the Pfizer and Moderna vaccine included people over 65, and results showed it to be safe and to work as well in older people as in younger ones.

“This vaccine has gone through testing and clinical trials to ensure it meets the highest safety standards. It also is safe to get if you already had the virus,” says a campaign to encourage people to get the shots by the American Health Care Association and National Center for Assisted Living, a combined trade group representing nursing homes and assisted-living communities.

The lead administrator for CMS, Seema Verma, reinforced the confidence in the shot for older patients, including those with health conditions, in a statement last week: “I urge states to prioritize nursing homes and vulnerable seniors in their distribution of the vaccine.”

The point is echoed by Dr. Sabine von Preyss-Friedman, chief medical officer of Avalon Health Care Group, which operates nursing homes, who said the new vaccines appear “safe and effective.”

Q: If restrictions are eased, should I visit right away?

A: The Pfizer and Moderna vaccines both require two injections — the initial shot and a booster three or four weeks later. Von Preyss-Friedman recommends waiting at least two weeks after the second shot to have a visit.

“You hope these vaccines work but these are elderly patients,” she said. “You want to err on the side of protection.”

She said that, ideally, the visitor would also be vaccinated as well. Since shots won’t be widely available for a few months, it may be best to wait until you get your vaccine. Until then she thinks nursing homes should consider visits on a case-by-case basis.

Q: Would visitors still need to wear a mask?

A: Absolutely, medical experts said. This is particularly true if they are not vaccinated, but even after they are vaccinated “until rates in the community go down,” said Dr. Joshua Uy, a geriatrician and associate professor at the University of Pennsylvania Medical School and the medical director of Renaissance Healthcare & Rehabilitation Center, a nursing home in Philadelphia.