All lanes are closed on the H-1 eastbound at the Kaonohi Overpass following a three-car collision today that left six people injured.

Honolulu police said a vehicle traveling eastbound in the freeway’s right lane collided with a second vehicle occupied by four people at about 10:21 a.m. The second vehicle subsequently struck a third vehicle with two occupants.

The third vehicle appeared to be having tire trouble and was slowing in traffic just prior to the collision, police said.

Paramedics responding to the scene treated and transported six people involved in the crash to a nearby hospital. Two occupants in the second vehicle were in critical condition and two were in serious condition. The two occupants of the third vehicle were in good condition.

The driver of the first vehicle was uninjured and remained at the scene.

Police initially closed three lanes of the H-1 eastbound near the Waialae on-ramp, later reopening the freeway after the scene was clear.

Speed, drugs, or alcohol do not appear to be factors in the collision at this time, though an investigation is ongoing, police said.