NEW YORK » Mike McCarthy promises there won’t be any bad memories plaguing his Green Bay Packers when they open the NFL season on Sept. 4 at Super Bowl champion Seattle.

The last time Green Bay visited CenturyLink Field was in Week 3 of the 2012 season, a 14-12 Seahawks victory clinched on what now is often dubbed the "Fail Mary." Russell Wilson’s desperation pass on the final play was called a touchdown reception for Golden Tate by the replacement officials.

A few days later, the lockout of the regular officials ended.

"This game won’t be about the past," he said. "It will be about the 2014 Green Bay Packers.

It’s the third straight season the Packers have traveled to face the defending Super Bowl champions.

"It’s a tremendous opportunity for our football team," Packers coach Mike McCarthy said. "We have experience playing in the kickoff opener three years ago, and we will draw on that. Obviously, being the visiting team this time presents new challenges. It will help sharpen our focus even more during training camp and the preseason."

That Thursday game is the first of four prime-time games on opening weekend. Also at night will be a Sunday matchup of AFC champion Denver and Peyton Manning hosting his former team, Indianapolis; and a Monday night doubleheader with the New York Giants at Detroit, followed by San Diego at Arizona.

The NFL will play three games in London: Dolphins-Raiders on Sept. 28; Lions-Falcons on Oct. 26; and Cowboys-Jaguars on Nov. 9. The Detroit-Atlanta game will kick off at 9:30 a.m. ET in an experiment to test the NFL’s audience draw on a Sunday morning.

A Saturday doubleheader in Week 16 has San Diego at San Francisco and Philadelphia at Washington.

For the first time, games in Weeks 5 through 10 can be flexed from Sunday afternoon to night, with a limit of two. Beginning with Week 11, a Sunday game can be moved to prime time each week. Also, a select number of Sunday afternoon games are being "cross-flexed," moving between CBS and Fox to potentially draw more viewers.

The Thanksgiving tripleheader features three strong division rivalries: Chicago at Detroit, Philadelphia at Dallas, and Seattle at San Francisco, a rematch of the memorable NFC title game last January.

That game will be played in 49ers’ new stadium in Santa Clara, Calif., which opens in Week 2 when they host Chicago in a Sunday night match.

Looking for the latest installment of Manning vs. Tom Brady? The Patriots host it on Sunday afternoon, Nov. 2.

And for those looking for the rematch of the Super Bowl, Seattle’s 43-8 rout of Denver, it’s on Sept. 21 at Seattle. Denver opens the season against three 2013 playoff teams: Indianapolis and Kansas City at home, then at the Seahawks.

"I think when you look at it, we have to start fast," Broncos general manager John Elway said. "We knew it was going to be a tough schedule playing the NFC West, and when we finish first in our division like we have the past three years, it is always going to be a tough schedule with a lot of good football teams on it."

Bye weeks begin in Week 4 when Arizona, Cincinnati, Cleveland, Denver, Seattle and St. Louis are off. They end in Week 12 when Carolina and Pittsburgh are idle.

The season ends Dec. 28 with all divisional games.