comscore Antibiotic shot found to lower infection risk after women give birth | Honolulu Star-Advertiser

Antibiotic shot found to lower infection risk after women give birth


A single injection of antibiotics significantly reduces the risk of infections when women who are giving birth require the aid of forceps or vacuum extraction, a new study concludes. The routine use of the prophylactic shot actually reduces antibiotic use in the long run, the study found.

British researchers randomly assigned 3,420 women who had operative vaginal births to one of two groups: The first received a single shot of Augmentin (amoxicillin and clavulanic acid) within six hours of giving birth, and the second a placebo saline shot. Then they tracked infections over the next six weeks. The study is in Lancet.

Compared with the placebo group, women who got the antibiotic had a 42% reduced risk for any infection, and a 56% lower risk of a body-wide infection. Antibiotic users had about half the risk of perineal wound infection compared with the placebo group, and they used less pain medication. The researchers calculated that for each additional 100 doses of antibiotic used preventively, 168 doses of antibiotics to treat infections would be saved.

“The evidence is very clear,” said the lead author, Dr. Marian Knight, a professor at the University of Oxford. “There is a benefit in a single dose of antibiotics after operational birth — less chance of infection, less chance of pain, less chance of problems with the wound. And we’re actually reducing the amount of antibiotics that would be used.”

Comments (0)

By participating in online discussions you acknowledge that you have agreed to the Terms of Service. An insightful discussion of ideas and viewpoints is encouraged, but comments must be civil and in good taste, with no personal attacks. If your comments are inappropriate, you may be banned from posting. Report comments if you believe they do not follow our guidelines.

Having trouble with comments? Learn more here.

Click here to see our full coverage of the coronavirus outbreak. Submit your coronavirus news tip.

Be the first to know
Get web push notifications from Star-Advertiser when the next breaking story happens — it's FREE! You just need a supported web browser.
Subscribe for this feature

Scroll Up