UPDATE: 10:50 a.m.

A 51-year-old woman was seriously injured when she was struck by a vehicle in a hit-and-run on South Vineyard Boulevard near Punchbowl Street early today, the Honolulu Police Department said.

The pedestrian was crossing the roadway when she was struck by an unknown vehicle traveling eastbound on South Vineyard Boulevard just before 5 a.m., police said.

The vehicle fled the scene without rendering aid to the woman.

Honolulu Emergency Medical Services personnel treated the pedestrian and took her in serious condition to a hospital.

Police said it appeared the woman was not in a crosswalk at the time of the collision.

It’s unknown whether speed, alcohol or drugs were factors in the crash.

Anyone who may have witnessed the hit-and-run is asked to call the Honolulu Police Department’s Traffic Division at 808-723-3413.

7:47 a.m.

Honolulu police have reopened the eastbound lanes of Vineyard Boulevard at the Punchbowl Street intersection.

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A 51-year-old woman was seriously injured after she was struck by a vehicle near The Queen’s Medical Center early today, the Honolulu Emergency Medical Services said.

EMS responded to Vineyard Boulevard near Punchbowl Street at about 5 a.m. Paramedics treated the pedestrian for multiple injuries and took her in serious condition to a hospital.

Honolulu police have temporarily closed the eastbound lanes of Vineyard Boulevard at the Punchbowl Street intersection.