BOISE, Idaho >> Deaths per day from the coronavirus in the U.S. are on the rise again, just as health experts had feared, and cases are climbing in nearly every state.

Average deaths per day across the country are up 10% over the past two weeks, from 721 to nearly 794 as of Sunday, according to data from Johns Hopkins University. Confirmed infections per day are rising in 47 states, and deaths are up in 34.

Health experts had warned that it was only a matter of time before deaths turned upward, given the record-breaking surge in cases engulfing the country. Deaths are a lagging indicator — that is, it generally takes a few weeks for people to sicken and die from the coronavirus.

Michael Osterholm, a University of Minnesota expert on infectious diseases who warned over the summer of a fall surge, said what’s happening now is a confluence of three factors: “pandemic fatigue” among people who are weary of hunkering down and are venturing out more; “pandemic anger” among those are don’t believe the scourge is a real threat; and cold weather, which is forcing more Americans indoors, where the virus can spread more easily.

“When you put those three together, we shouldn’t be surprised what we’re seeing,” Osterholm said.

The virus is blamed for more than 8.6 million confirmed infections and over 225,000 deaths in the U.S., the highest such totals anywhere in the world.

Deaths are still well below the U.S. peak of over 2,200 a day in late April. But experts are warning of a grim fall and winter, with a widely cited model from the University of Washington projecting about 386,000 dead by Feb. 1. A vaccine is unlikely to become widely available until mid-2021.

The seven-day rolling average for daily new cases hit a record high on Sunday of 68,767, according to Johns Hopkins, eclipsing the previous mark of 67,293, set in mid-July. The U.S. recorded more than 80,000 new cases on both Friday and Saturday — the highest marks ever — though testing has expanded dramatically over the course of the outbreak, making direct comparisons problematic.

The true number of infections is thought to be far higher because many Americans have not been tested, and studies suggest people can be infected without feeling sick.

Fears about the virus’s toll on the economy — and fading hopes that Washington will be able to deliver more relief anytime soon — sent stocks into a slump in afternoon trading on Wall Street. The S&P 500 was 2.3% lower and on track for its worst day in more than a month. The Dow Jones Industrial Average was down more than 800 points, or almost 3%, in midday trading today.

In the Texas border city of El Paso, authorities instructed people to stay home for two weeks and imposed a 10-p.m.-to-5-a.m. curfew because of a surge that has overwhelmed hospitals. The state is converting part of the city’s civic center into a hospital.

Violators of the curfew are subject to $500 fines, though the order does not apply to people who are going to or from work or are out for other essential reasons, such as food shopping and medical care.

“We are in a crisis stage,” El Paso County Judge Ricardo Samaniego, the county’s top elected official, as he issued the stay-at-home order over the weekend.

Today, the county reported a record high in daily cases, with 1,443. The county had 853 patients hospitalized because of the virus, up from 786 a day earlier. The state has provided over 900 medical personnel to El Paso, some of whom will staff the convention center site.

Just last week, the president during the last presidential debate downplayed the virus’s effect in Texas, saying: “There was a very big spike in Texas, it’s now gone.”

On Sunday, White House chief of staff Mark Meadows said that “we’re not going to control the pandemic” and that the focus should be on containment and treatment.

President Donald Trump, who spent several days in the hospital after contracting the virus, said repeatedly over the weekend that the country is “rounding the turn.” His remarks came amid another outbreak in the White House inner circle. Several close aides to Vice President Mike Pence tested positive, including his chief of staff.

In Kentucky, the state shattered its record for the number of new cases per week, with 9,335.

“We must do better,” Democratic Gov. Andy Beshear said, adding that he plans to make recommendations soon for counties with high rates of infection.

Arizona is seeing a slow but steady increase in the average number of COVID-19 cases reported each day, reversing a decline in August and September. Deaths have reached nearly 5,900.

In Massachusetts, where Republican Gov. Charlie Baker has won accolades for helping to contain the virus, the Marblehead school district decided to shift to fully remote learning after students attended a house party where they shared drinks and didn’t wear masks.

Marblehead Superintendent John Buckey said in a letter to families on Sunday that he understood “young people’s desire to be together, as far away from adults as possible,” but that ignoring the rules was “potentially harming the community at large.”

The University of Minnesota’s Osterholm has been predicting the darkest days will be in the weeks or months ahead. He said he expects increased competition for drugs and shortages of hospital specialists, N95 masks and other protective gear.

A strong national response plan was needed, along with consistent messaging that emphasized mask wearing and other preventive measures, Osterholm said.

“But our response has been… I don’t know what our response has been,” he said.