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Drug execs face Capitol Hill questions on COVID-19 vaccine supply

NELVIN C. CEPEDA/THE SAN DIEGO UNION-TRIBUNE VIA ASSOCIATED PRESS
                                A Scripps health official drew from a vial of the COVID-19 vaccine, Feb. 12, prior to administering it at their new drive-thru vaccination site at the Del Mar Fairgrounds in Del Mar, Calif. Executives from the major COVID-19 vaccine producers are set, today, to answer questions from Congress about expanding the supply of shots needed to curb the pandemic that has killed more than 500,000 Americans.
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NELVIN C. CEPEDA/THE SAN DIEGO UNION-TRIBUNE VIA ASSOCIATED PRESS

A Scripps health official drew from a vial of the COVID-19 vaccine, Feb. 12, prior to administering it at their new drive-thru vaccination site at the Del Mar Fairgrounds in Del Mar, Calif. Executives from the major COVID-19 vaccine producers are set, today, to answer questions from Congress about expanding the supply of shots needed to curb the pandemic that has killed more than 500,000 Americans.

WASHINGTON >> Executives from the major COVID-19 vaccine producers are set to answer questions from Congress today about expanding the supply of shots needed to curb the pandemic that has killed more than 500,000 Americans.

The hearing comes as U.S. vaccinations continue to accelerate after a sluggish start and recent disruptions caused by winter weather. But state health officials say demand for inoculations still vastly outstrips the limited weekly shipments provided by the federal government.

The Energy and Commerce Committee panel began hearing testimony from the five companies with contracts to supply COVID-19 shots to the U.S.: Pfizer, Moderna, Johnson & Johnson, AstraZeneca and Novavax.

“The most pressing challenge now is the lack of supply of vaccine doses,” Rep. Diana DeGette said as she opened the hearing. “Some of the companies here today are still short of the number of doses they promised to initially deliver when they last testified before this subcommittee in July.”

DeGette, a Colorado Democrat, chairs the investigative subcommittee that convened today’s hearing. She urged “a straightforward assessment of where the manufacturing process stands.”

The pharmaceutical executives are expected to face pointed questions about whether shortages of raw materials, manpower or funding are limiting the pace of manufacturing. Lawmakers are also expected to ask whether further use of the Defense Production Act — a Cold War-era law used to compel private-sector manufacturing — could help speed the process.

In written testimony released Monday, company executives did not describe shortages or other bottlenecks that have not already been addressed.

More than 75 million doses of the two-shot-regimen vaccines from Pfizer and Moderna have already been distributed to states, with nearly 14% of Americans receiving at least an initial dose. Pfizer expects to be shipping more than 13 million doses a week by the middle of March.

New Brunswick, N.J.-based J&J revealed in its testimony that it will be able to supply 20 million U.S. doses of its single-shot COVID-19 vaccine by the end of March, assuming it gets the green light from federal regulators. The company has promised to supply 100 million doses to the U.S. government by the end of June.

The company had previously released few details on its initial supplies, though White House officials cautioned last week that they would be limited.

J&J Vice President Richard Nettles plans to tell lawmakers the company faces “significant challenges” in scaling up its vaccine, due to its “highly complex” manufacturing process. Nettles states that the company remains on track to supply the promised U.S. doses and 1 billion globally by the end of 2021.

The Food and Drug Administration is expected to grant emergency approval for J&J’s vaccine as soon as this weekend, providing the first one-shot option to protect against the virus.

Despite current constraints, federal health officials say the U.S. is on the cusp of a supply breakthrough, with a total of 600 million doses slated for delivery by late July. That would be enough to deliver on the government’s goal to provide enough shots for every American adult.

Even with no manufacturing or supply interruptions, other issues could delay or block the U.S. from vaccinating 70% to 80% of its population — the critical threshold needed to neutralize COVID-19 spread.

About 1 in 3 Americans say they definitely or probably will not get the vaccine, according to a recent poll from The Associated Press-NORC Center for Public Affairs Research. Concerns about safety were the reason most frequently cited for vaccine hesitancy, despite few serious side effects reported with the currently available vaccines.

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